Vitamin D levels do not predict the stage of hepatic fibrosis in patients with non-alcoholic fatty liver disease: A PRISMA compliant systematic review and meta-analysis of pooled data

doi:10.4254/wjh.v10.i1.142

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World Journal of Hepatology

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World J Hepatol. Jan 27, 2018; 10(1): 142-154
Published online Jan 27, 2018. doi: 10.4254/wjh.v10.i1.142

Table 4 Relationship of vitamin D to liver fibrosis in non-alcoholic fatty liver disease

Author/year/Ref	(n), 25-OH(D) Mean ± SD F0	(n), 25-OH(D) Mean ± SD F1	(n), 25-OH(D) Mean ± SD F2	(n), 25-OH(D) Mean ± SD F3	(n), 25-OH(D) Mean ± SD F4	P value
Patel et al[32], 2016	(39) 24.4 ± 10.4	(78) 26.5 ± 8.9	(55) 29.1 ± 12.5	(63) 30.7 ± 14.1	(9) 20.2 ± 20.2	0.028
Targher et al[26], 2007	(16) 20.8 ± 8.4	(10) 14.4 ± 9.2	(7) 10.0 ± 10.0	(6) 6.0 ± 10.8	0	0.01
Anty et al[27], 2016	(50) 20.04 ± 7.81	(233) 19.91 ± 9.12	(98) 18.28 ± 9.58	(15) 16.71 ± 9.86	(2) 25 ± 10.18	0.01
Luger et al[30], 2016	(2) 15.6 ± 5.2	(30) 15.2 ± 6.0	(8) 15.6 ± 4.4	(4) 17.6 ± 7.6	(2) 20.4 ± 4.4	0.792
Bril et al[29], 2015	(61) 20.5 ± 10.4	(75) 24.2 ± 15.1	(22) 20.8 ± 12.1	(22) 25.5 ± 12.2	(5) 21.1 ± 6.9	0.27
Barchetta et al[28], 2012	(1) 20.5	(10) 23.5 ± 14.4	(7) 16.25 ± 6.1	(6) 28.8 ± 14.9	(1) 17.3	0.56

n: Number of subjects; 25-OH(D): 25-hydroxylvitamin D; SD: Standard deviation; F0-F4: Severity score of hepatic fibrosis.

Citation: Saberi B, Dadabhai AS, Nanavati J, Wang L, Shinohara RT, Mullin GE. Vitamin D levels do not predict the stage of hepatic fibrosis in patients with non-alcoholic fatty liver disease: A PRISMA compliant systematic review and meta-analysis of pooled data. World J Hepatol 2018; 10(1): 142-154
URL: https://www.wjgnet.com/1948-5182/full/v10/i1/142.htm
DOI: https://dx.doi.org/10.4254/wjh.v10.i1.142