Aggressive liver resection including major-vessel resection for colorectal liver metastases

Table 3 Univariate analysis of predictive factors for combined major-vessel resection

Variables		Conventional (n = 346)	Combined (n = 25)	P value
		n (%)	n (%)
Patient-related
Age (yr)	≤ 64	179 (52)	14 (56)	0.84
	≥ 65	167 (48)	11 (44)
Gender	Male	209 (60)	14 (56)	0.68
	Female	137 (40)	11 (44)
Primary-related
Site	Colon	204 (59)	19 (76)	0.14
	Rectum	142 (41)	6 (24)
Histology	Moderate	223 (64)	14 (56)	0.40
	Others	123 (36)	11 (44)
Dukes stage	A/B	120 (35)	4 (16)	0.08
	C	226 (65)	21 (84)
Liver-related
Hepatectomy	Initial	296 (86)	16 (64)	< 0.01
	Repeat	50 (14)	9 (36)
Distribution	Unilobar	213 (62)	12 (48)	0.21
	Bilobar	133 (38)	13 (52)
Number	≤ 2	222 (64)	14 (56)	0.52
	≥ 3	124 (36)	11 (44)
Maximum tumor size (mm)	≤ 30	197 (57)	6 (24)	< 0.01
	> 30	149 (43)	19 (76)
Prehepatectomy CEA (ng/mL)	< 10	175 (54)	17 (68)	0.21
	≥ 10	150 (46)	8 (32)
Treatment-related
Extent of hepatectomy	Major	112 (32)	13 (52)	0.05
	Minor	234 (68)	12 (48)
PVE	Performed	44 (13)	7 (28)	0.06
	Not performed	302 (87)	18 (72)
Staged procedure	Performed	20 (6)	1 (4)	> 0.99
	Not performed	326 (94)	24 (96)
Hepatectomy with ablation	Performed	26 (8)	4 (16)	0.13
	Not performed	320 (92)	21 (84)
Prehepatectomy chemotherapy	Performed	63 (18)	11 (44)	< 0.01
	Not performed	283 (82)	14 (56)

Moderate: Moderately differentiated adenocarcinoma; CEA: Carcinoembryonic antigen; PVE: Portal vein embolization.