Next-generation sequencing traces human induced pluripotent stem cell lines clonally generated from heterogeneous cancer tissue

Table 7 Allelic depth of single-nucleotide variants among the matched adjacent non-cancerous tissue, the starting cancer tissue, and the cancer tissue-derived induced pluripotent stem cell lines

	Allelic depth of SNVs
SNV No.	NCC1	CC1	CC1-1	CC1-2	CC1-7	CC1-8	CC1-9	CC1-11	CC1-12	CC1-17	CC1-18	CC1-25
1	250|0	246|0	232|0	250|0	250|0	250|0	250|0	248|0	250|0	250|0	129|121	250|0
2	249|0	240|0	240|0	248|0	248|1	250|0	129|121	248|0	242|0	250|0	250|0	244|0
3	246|0	247|2	249|0	238|1	246|0	248|0	233|0	241|0	238|1	241|0	245|0	132|106
4	250|0	239|0	243|0	248|0	245|0	120|129	250|0	236|0	250|0	250|0	250|0	249|0
5	216|0	150|0	75|79	189|0	184|0	180|0	200|1	131|0	176|0	221|0	207|0	179|0
6	249|0	238|0	250|0	132|114	250|0	250|0	242|0	248|0	248|0	250|0	250|0	249|0
7	250|0	248|0	250|0	250|0	245|0	246|0	245|0	135|111	249|0	250|0	250|0	246|1
8	233|0	240|1	243|0	250|0	245|0	242|0	247|0	248|0	132|113	240|1	247|0	241|0
9	249|0	246|2	250|0	250|0	249|0	220|30	244|0	249|0	250|0	249|1	250|0	249|0
10	247|0	177|0	188|0	119|121	198|0	244|0	241|0	176|0	221|0	224|0	249|0	174|0
11	246|1	172|0	181|0	208|0	209|0	198|0	189|0	175|0	244|0	182|0	233|0	95|87
12	249|1	195|54	241|0	249|0	249|0	249|1	249|0	250|0	249|0	250|0	249|1	250|0
13	137|0	91|10	79|0	131|0	102|0	103|0	103|0	83|0	106|0	111|0	142|0	90|0

NCC1: The matched adjacent non-cancerous tissue; CC1: The starting cancer tissue of the induced pluripotent stem cell lines; CC1-1 to CC1-25: Each induced pluripotent stem cell line; SNV: Single-nucleotide variant.