Use of platelet lysate for bone regeneration - are we ready for clinical translation?

Figure 1 The enhancement of mesenchymal stem cell colony formation in platelet lysate-cultured bone marrow aspirates from a single patient. Day-14 colonies formed from 200 μL of fresh BM aspirate seeded on plastic culture dish with either 100 mL/L FCS (A) or 100 mL/L PL (B). Higher magnification (40 ×) of individual colonies grown in 100 mL/L FCS (C) or 100 mL/L PL (D). Quantified analysis of the number of colonies (E). The average size of colonies in pixels (F). Colony number and size were analysed using NIS Elements BR Nikon software. BM: Bone marrow; PL: Platelet lysate; FCS: Fetal calf serum.