Stem/progenitor cells and obstructive sleep apnea syndrome - new insights for clinical applications

Table 2 Circulating endothelial progenitor cells studies in patients with obstructive sleep apnea syndrome

Ref.	Study design	EPCs phenotype	OSAS effect on EPCs number
de la Peña et al[60]	Adults, men, flow cytometry	CD34+VEGFR2+	Reduced number
Jelic et al[61]	Adults, both genders, flow cytometry	CD34+CD133+VEGFR2+	Reduced number
Jelic et al[62]	Adults, both genders, flow cytometry	CD34+CD133+VEGFR2+	Reduced number
Murri et al[63]	Adults, both genders, flow cytometry	CD45-CD34+CD133+VEGFR2+	Reduced number
Kheirandish-Gozal et al[64]	Children, both genders, flow cytometry	CD34+CD133+VEGFR2+	Reduced number
Martin et al[65]	Adults, both genders, flow cytometry	CD34+CD133+CD45dim	Unchanged number
Yun et al[66]	Adults, both genders, endothelial colony forming units assay	-	Unchanged number
Simpson et al[67]	Adults, men, flow cytometry	CD34+KDR+	Unchanged number
		CD45-CD34+KDR+
Kizawa et al[68]	Adults, men, flow cytometry	CD133+CD34+CD202b+CD45-	Increased number
Lui et al[69]	Adults, both genders, flow cytometry	CD34+	Increased number
Chou et al[70]	Adults, both genders, flow cytometry	CD34+	Increased number

EPC: Endothelial progenitor cell; OSAS: Obstructive sleep apnea syndrome.