Copyright
©The Author(s) 2016.
World J Stem Cells. Jan 26, 2016; 8(1): 1-12
Published online Jan 26, 2016. doi: 10.4252/wjsc.v8.i1.1
Published online Jan 26, 2016. doi: 10.4252/wjsc.v8.i1.1
Table 1 The use of bone morphogenetic proteins in the induction of chondrogenesis and osteogenesis in mesenchymal stem cells in vitro
| BMP type and conditions | Cell type | Ref. |
| Chondrogenesis | ||
| BMP2 (micromass + TGF-β3) | BM MSCs | [41,45,46] |
| BMP2 (3D alginate beads) | BM MSCs | [37] |
| BMP4 (micromass + TGF-β3) | BM MSCs | [41] |
| BMP6 (micromass + TGF-β3) | BM MSCs | [41] |
| BMP7 (micromass + TGF-β3) | BM MSCs | [45,46] |
| BMP9 (3D alginate beads) | BM MSCs | [37] |
| BMP2 (3D agarose) | Synovial explant MSCs | [43] |
| BMP7 (3D agarose) | Synovial explant MSCs | [43] |
| BMP7 (monolayer) | Adipose derived MSCs | [44] |
| BMP7 (monolayer + Asc) | C3H10T1/2 (multipotent fibroblasts) | [54] |
| BMP2 (monolayer) | MC615 (chondrocyte precursors) | [53] |
| BMP4 (monolayer) | MC615 (chondrocyte precursors) | [53] |
| Osteogenesis | ||
| BMP2 (monolayer) | Adipose derived MSCs | [44] |
| BMP2 (monolayer + Dexa and Asc) | BM MSCs | [56,62] |
| BMP3 (monolayer + Dexa and Asc) | BM MSCs | [62] |
| BMP4 (monolayer + Dexa and Asc) | BM MSCs | [62] |
| BMP5 (monolayer + Dexa and Asc) | BM MSCs | [62] |
| BMP6(monolayer + Dexa and Asc) | BM MSCs | [62] |
| BMP6 (monolayer) | BM MSCs | [58] |
| BMP7 (monolayer + Dexa and Asc) | BM MSCs | [62] |
| BMP8a (monolayer + Dexa and Asc) | BM MSCs | [62] |
| BMP7 (monolayer + Asc) | C3H10T1/2 (multipotent fibroblasts) | [55] |
| BMP7 (monolayer + Asc) | MC3T3-E1 (committed osteoblasts) | [54] |
- Citation: Scarfì S. Use of bone morphogenetic proteins in mesenchymal stem cell stimulation of cartilage and bone repair. World J Stem Cells 2016; 8(1): 1-12
- URL: https://www.wjgnet.com/1948-0210/full/v8/i1/1.htm
- DOI: https://dx.doi.org/10.4252/wjsc.v8.i1.1