Common stemness regulators of embryonic and cancer stem cells

doi:10.4252/wjsc.v7.i9.1150

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Oct 26, 2015 (publication date) through Nov 24, 2024

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Oct 26, 2015; 7(9): 1150-1184
Published online Oct 26, 2015. doi: 10.4252/wjsc.v7.i9.1150

Table 1 Biomarkers of pluripotency in mouse and human embryonic stem cells

Biomarker	Role in mESC	Role in hESC
Oct4	Pluripotency[200]	Pluripotency[4]
Sox2	Pluripotency[215]	Pluripotency[4]
Nanog	Pluripotency[227]	Pluripotency[4]
Klf4	Pluripotency[253,255]	Pluripotency[253]
c-Myc	Pluripotency[190]	Pluripotency[190]
SSEA1/CD15	Pluripotency[18,19]	Not expressed
SSEA 3, 4	Not expressed	Pluripotency[20,22]
TRA-1-68	Not expressed	Pluripotency[24]
TRA-1-81	Not expressed	Pluripotency[24]
Cripto-1	Pluripotency[28,474]	Pluripotency[28,474]

hESC: Human embryonic stem cell; mESCs: Mouse embryonic stem cells; SSEA: Stage specific embryonic antigens; TRA: Tumor rejection antigens.

Citation: Hadjimichael C, Chanoumidou K, Papadopoulou N, Arampatzi P, Papamatheakis J, Kretsovali A. Common stemness regulators of embryonic and cancer stem cells. World J Stem Cells 2015; 7(9): 1150-1184
URL: https://www.wjgnet.com/1948-0210/full/v7/i9/1150.htm
DOI: https://dx.doi.org/10.4252/wjsc.v7.i9.1150