Fetal kidney stem cells ameliorate cisplatin induced acute renal failure and promote renal angiogenesis

Figure 8 Early angiogenic effect of administered fetal kidney stem cells in cisplatin injured kidney. Representative immunoblots showing the expression of hypoxia-inducible factor (HIF)-1α, vascular endothelial growth factor (VEGF) and endothelial nitric oxide synthase (eNOS) in saline and fetal kidney stem cells (fKSC) treated groups on day 3 after fKSC therapy (A-D). Bar diagrams showing densitometric quantification of the expression of HIF-1α (B), VEGF (C) and eNOS (D). Comparative gene expression ratio was calculated by referring each gene to β-actin as an internal control. Densitometric analysis applied for comparison of relative protein expression and represented in densitometric arbitrary units (a. u.). Values expressed mean ± SE. ^aP < 0.05 for fKSC vs saline treated group.