Role of Hox genes in stem cell differentiation

Table 2 Hox genes play a role in various differentiations

Differentiation	Hox gene expression	Ref.
Adipogenesis	a4, a7, d4, A1, A4, A5, A10, B8, C4, C8 ↓, C13	[60-63]
Chondrogenesis	a2 ↓, a11, c8 ↓, d4 ↓, d11, D9 ↑, D11, D13 ↑	[65,66,70-73,77,78]
Osteogenesis	a2 ↑, a10, d9 ↓, d12, d13, A10	[82,86,87,89]
Tendon differentiation	A13, D13	[90]
Cardiomyocyte differentiation	a10, A1	[75,95-98,100]
Smooth muscle cell differentiation	a6-10, b6-10, c6-10, d6-10, A11, A13, B7, C6, C8	[50,101,102]
Endothelial cell differentiation	a3 ↓, a5 ↑, d3 ↓, d10 ↑, A7 ↑, A9 ↑, A13 ↑, B2 ↑, B3 ↑, B4 ↑, B5 ↑, B6 ↑, B13 ↑	[20,106-108]
Neurogenesis	a2, b1, B4	[110-112,114-116]

Small capitals: Murine; Large capitals: Human and chicken; ↑: Up-regulation; ↓: Down-regulation.