Using induced pluripotent stem cells as a tool for modelling carcinogenesis

doi:10.4252/wjsc.v7.i2.461

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Mar 26, 2015; 7(2): 461-469
Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.461

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Figure 1 Schematic illustrating normal stem cell expansion and the cancer stem cell model. Normal stem, transit-amplifying or differentiated cells can undergo oncogenic reprogramming resulting in generation of cancer stem cells (CSCs). Non-CSCs also demonstrate plasticity and can dedifferentiate to CSCs.

Citation: Curry EL, Moad M, Robson CN, Heer R. Using induced pluripotent stem cells as a tool for modelling carcinogenesis. World J Stem Cells 2015; 7(2): 461-469
URL: https://www.wjgnet.com/1948-0210/full/v7/i2/461.htm
DOI: https://dx.doi.org/10.4252/wjsc.v7.i2.461