Copyright
©The Author(s) 2015.
World J Stem Cells. Mar 26, 2015; 7(2): 461-469
Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.461
Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.461
Figure 1 Schematic illustrating normal stem cell expansion and the cancer stem cell model.
Normal stem, transit-amplifying or differentiated cells can undergo oncogenic reprogramming resulting in generation of cancer stem cells (CSCs). Non-CSCs also demonstrate plasticity and can dedifferentiate to CSCs.
- Citation: Curry EL, Moad M, Robson CN, Heer R. Using induced pluripotent stem cells as a tool for modelling carcinogenesis. World J Stem Cells 2015; 7(2): 461-469
- URL: https://www.wjgnet.com/1948-0210/full/v7/i2/461.htm
- DOI: https://dx.doi.org/10.4252/wjsc.v7.i2.461