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Copyright ©The Author(s) 2015.
World J Stem Cells. Mar 26, 2015; 7(2): 461-469
Published online Mar 26, 2015. doi: 10.4252/wjsc.v7.i2.461
Figure 1
Figure 1 Schematic illustrating normal stem cell expansion and the cancer stem cell model. Normal stem, transit-amplifying or differentiated cells can undergo oncogenic reprogramming resulting in generation of cancer stem cells (CSCs). Non-CSCs also demonstrate plasticity and can dedifferentiate to CSCs.