Induction of CXC chemokines in human mesenchymal stem cells by stimulation with secreted frizzled-related proteins through non-canonical Wnt signaling

doi:10.4252/wjsc.v7.i11.1262

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Dec 26, 2015; 7(11): 1262-1273
Published online Dec 26, 2015. doi: 10.4252/wjsc.v7.i11.1262

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Figure 4 Modulation of secreted frizzled-related protein-stimulated induction of CXCL8 mRNA. sFRP1/2-stimulated CXCL8 mRNA expression is suppressed in the presence of the PLC inhibitor U73122 suggesting that signaling is via the Wnt/calcium non-canonical pathway (values are mean ± SD). ^aP < 0.05 vs HMSCGM-treated levels. sFRP1/2: Secreted frizzled-related protein 1/2; PLC: Phospholipase C.

Citation: Bischoff DS, Zhu JH, Makhijani NS, Yamaguchi DT. Induction of CXC chemokines in human mesenchymal stem cells by stimulation with secreted frizzled-related proteins through non-canonical Wnt signaling. World J Stem Cells 2015; 7(11): 1262-1273
URL: https://www.wjgnet.com/1948-0210/full/v7/i11/1262.htm
DOI: https://dx.doi.org/10.4252/wjsc.v7.i11.1262