Fetal vs adult mesenchymal stem cells achieve greater gene expression, but less osteoinduction

Figure 8 Histological examination of thighs after osteoinduction. A: Arrow points at new periosteal bone and cortical thickening of Ad-BMP2-aMSC treated mouse; B: Corresponding H and E photomicrograph showing normal bone formation with new bone marrow adjacent to the periosteum; C: Radiograph of control aMSC injected mouse and corresponding; D: H and E slide; E: toluidine blue-stained slide showing a nodule of MSCs and no bone or cartilage formation. Scale bar = 100 μm. BMP2: Bone morphogenic protein 2; aMSCs: Adult mesenchymal stem cells.