Current progress in use of adipose derived stem cells in peripheral nerve regeneration

Table 2 Table of various neuron markers their distributions and function adapted from[99]

Marker	Distribution	Protein function
GFAP	Mature cells of glial origin	Specifically found in astroglial cells
MAP 2	Mature marker of neurones	Thought to be involved in microtubule assembly during neurogenesis
Nestin	Developing nervous system, myogenic, endothelial and hepatic cells	Intermediate filament protein expressed in multiple tissues
NF-70	Most PNS neurones	Structural protein supporting large axons and synapses
NSE	Early neuronal marker	Three variants: α, β, γ with only the γ isoenzyme expressed in neuronal tissue
S100	Cytoplasm of SCs, astrocytes and astrogliosis	Non-specific cell marker involved in multiple cell processes including cell cycle progression and differentiation
Synaptophisin	Brain synaptic vesicles	Directs vesicle associated membrane protein-2 to intracellular compartments
TAU	Axons	βNeuronal microtubule associated protein stabilising microtubules and link to signalling pathways to cytoskeleton
βIII-tubulin	Central and peripheral nervous system axons	β tubulins heterodimerize to form microtubules involved in axon guidance

GFAP: Glial fibrillary acid protein; MAP2: Microtubule associated protein-2; NSE: Neuron specific enolase; PNS: Peripheral nervous system; SCs: Schwann cells.