Copyright
©The Author(s) 2015.
World J Stem Cells. Jan 26, 2015; 7(1): 51-64
Published online Jan 26, 2015. doi: 10.4252/wjsc.v7.i1.51
Published online Jan 26, 2015. doi: 10.4252/wjsc.v7.i1.51
Marker | Distribution | Protein function |
GFAP | Mature cells of glial origin | Specifically found in astroglial cells |
MAP 2 | Mature marker of neurones | Thought to be involved in microtubule assembly during neurogenesis |
Nestin | Developing nervous system, myogenic, endothelial and hepatic cells | Intermediate filament protein expressed in multiple tissues |
NF-70 | Most PNS neurones | Structural protein supporting large axons and synapses |
NSE | Early neuronal marker | Three variants: α, β, γ with only the γ isoenzyme expressed in neuronal tissue |
S100 | Cytoplasm of SCs, astrocytes and astrogliosis | Non-specific cell marker involved in multiple cell processes including cell cycle progression and differentiation |
Synaptophisin | Brain synaptic vesicles | Directs vesicle associated membrane protein-2 to intracellular compartments |
TAU | Axons | βNeuronal microtubule associated protein stabilising microtubules and link to signalling pathways to cytoskeleton |
βIII-tubulin | Central and peripheral nervous system axons | β tubulins heterodimerize to form microtubules involved in axon guidance |
- Citation: Zack-Williams SD, Butler PE, Kalaskar DM. Current progress in use of adipose derived stem cells in peripheral nerve regeneration. World J Stem Cells 2015; 7(1): 51-64
- URL: https://www.wjgnet.com/1948-0210/full/v7/i1/51.htm
- DOI: https://dx.doi.org/10.4252/wjsc.v7.i1.51