Fetal vs adult mesenchymal stem cells achieve greater gene expression, but less osteoinduction

doi:10.4252/wjsc.v7.i1.223

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Jan 26, 2015; 7(1): 223-234
Published online Jan 26, 2015. doi: 10.4252/wjsc.v7.i1.223

Table 1 Bone morphogenic protein 2 expression from adenoviral-transduced mesenchymal stem cells

Medium	O.D. (Mean ± SD)	Corrected O.D.	BMP2 (pg/cell-day)	Total BMP2 injected (ng/day)
fMSC	0.043 ± 0.004	-	-	-
aMSC	0.031 ± 0.002	-	-	-
Ad-BMP2-fMSC	2.99 ± 0.33	2.95	0.02	32.8^b
Ad-BMP2-aMSC	1.69 ± 0.27	1.66	0.01	18.5

^bP < 0.01 Ad-BMP2-fMSC vs Ad-BMP2-aMSC. BMP2: Bone morphogenic protein 2; MSCs: Mesenchymal stem cells; Ad-GFP: E1-A-deleted-green fluorescent protein; fMSCs: Fetal mesenchymal stem cells; aMSCs: Adult mesenchymal stem cells.

Citation: Santiago-Torres JE, Lovasz R, Bertone AL. Fetal vs adult mesenchymal stem cells achieve greater gene expression, but less osteoinduction. World J Stem Cells 2015; 7(1): 223-234
URL: https://www.wjgnet.com/1948-0210/full/v7/i1/223.htm
DOI: https://dx.doi.org/10.4252/wjsc.v7.i1.223