Regulated genes in mesenchymal stem cells and gastric cancer

Table 3 Gene expression alterations of epithelial-mesenchymal transition-related genes in mesenchymal stem cells and diffuse-type gastric cancer

Gene symbol	Gene name	P value	Ratio of diffuse-type GC to MSCs	Probe set ID
TWIST1	Twist family bHLH transcription factor 1	0.0004	0.2	213943_at
PRRX1	Paired related homeobox 1	1.00E-05	0.3	226695_at
ZEB2	Zinc finger E-box binding homeobox 2	0.027	2.1	203603_s_at
		0.03	1.7	228333_at
		6.00E-05	3.9	235593_at
TJP1	Tight junction protein 1	0.184	1.2	202011_at
		0.795	1	214168_s_at
CTNNB1	Catenin (cadherin-associated protein), beta 1, 88 kDa	0.001	9.6	223679_at
VIM	Vimentin	0.031	4.7	1555938_x_at
		0.016	0.7	201426_s_at
FN1	Fibronectin 1	0.204	0.6	1558199_at
		0.015	0.7	210495_x_at
		0.004	0.7	211719_x_at
		0.001	0.6	212464_s_at
		4.00E-08	0.04	214701_s_at
		1.00E-10	0.02	214702_at
		0.008	0.7	216442_x_at
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.187	1.2	207163_s_at
AKT2	v-akt murine thymoma viral oncogene homolog 2	8.00E-09	3.1	225471_s_at
		0.002	4.4	226156_at
		0.0006	5.6	236664_at
		0.0006	7.6	1560689_s_at
AKT3	v-akt murine thymoma viral oncogene homolog 3	0.0006	6.2	242876_at
		0.008	0.6	212607_at
		0.549	1.2	212609_s_at
		0.385	0.8	219393_s_at
		0.772	1.1	222880_at
		0.0003	0.5	242879_x_at
SFN	Stratifin	0.003	66	33322_i_at
		0.008	111	33323_r_at
EPCAM	Epithelial cell adhesion molecule	0.0009	725	201839_s_at
F11R	F11 receptor	0.0004	35	221664_s_at
		0.002	21	222354_at
		0.0009	201	223000_s_at
		0.012	25	224097_s_at
GJB2	Gap junction protein, beta 2, 26 kDa	0.023	69	223278_at
LEF1	Lymphoid enhancer-binding factor 1	0.002	26	221558_s_at
JUN	Jun proto-oncogene	0.042	4.8	201464_x_at
		0.022	5.1	201466_s_at
		0.079	3.8	201465_s_at
		0.019	4.1	213281_at
TGFB1	Transforming growth factor, beta 1	0.002	2	203085_s_at
TGFB2	Transforming growth factor, beta 2	0.07	0.4	209909_s_at
		0.055	0.6	220407_s_at
		0.588	0.8	228121_at
TGFB3	Transforming growth factor, beta 3	0.015	6.8	209747_at
SP1	Sp1 transcription factor	0.0002	3.4	224754_at
		2.00E-05	2.7	224760_at
HMGA2	High mobility group AT-hook 2	0.003	0.3	208025_s_at
ITGA5	Integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.007	0.5	201389_at
OCLN	Occludin	0.0008	8	231022_at
		0.012	9.4	235937_at
		0.027	11	209925_at
		0.0045	11	227492_at
CXADR	Coxsackie virus and adenovirus receptor	0.013	265	203917_at
		0.014	297	226374_at
		0.021	75	239155_at
KRT8	Keratin 8	0.012	128	209008_x_at

RGS: Regulator of G-protein signaling; MSCs: Mesenchymal stem cells; GC: Gastric cancer.