Regulated genes in mesenchymal stem cells and gastric cancer

Table 2 Gene expression alterations of stem cell-related genes in mesenchymal stem cells and diffuse-type gastric cancer

Gene symbol	Gene name	P value	Ratio of diffuse-type GC to MSCs	Probe set ID
NANOG	Nanog homeobox	0.0037	14.9	220184_at
SUZ12	SUZ12 polycomb repressive complex 2 subunit	0.0022	35.4	1566191_at
TNFRSF8	Tumor necrosis factor receptor superfamily, member 8	0.0126	1.98	206729_at
CD9	CD9 molecule	0.0012	3.44	201005_at
ICAM3	Intercellular adhesion molecule-3	0.0143	2.69	204949_at
CD200	CD200 molecule	0.0013	4.79	209583_s_at
		0.0002	4.35	209582_s_at
THY1	Thy-1 cell surface antigen	0.0081	0.61	208850_s_at
		0.0301	0.79	208851_s_at
		0.0024	0.67	213869_x_at

Genes related to stem cells in the literature are shown with their gene expression alterations in MSCs and diffuse-type GC. NANOG and SUZ12, which have been found by gene expression analysis to be involved in MSC invasion was up-regulated in diffuse-type GC compared to MSCs. RGS: Regulator of G-protein signaling; MSCs: Mesenchymal stem cells; GC: Gastric cancer.