Copyright
©The Author(s) 2015.
World J Stem Cells. Jan 26, 2015; 7(1): 208-222
Published online Jan 26, 2015. doi: 10.4252/wjsc.v7.i1.208
Published online Jan 26, 2015. doi: 10.4252/wjsc.v7.i1.208
Table 1 Gene expression alterations of regulator of G-protein signaling family genes in mesenchymal stem cells and diffuse-type gastric cancer
Gene symbol | Detailed description | P value | Ratio of diffuse-type GC to MSCs | Probe set ID |
RGS1 | Immune response / signal transduction / adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway / negative regulation of signal transduction / termination of G-protein coupled receptor signaling pathway / positive regulation of GTPase activity | 0.013 | 1004 | 202988_s_at |
0.001 | 13808 | 216834_at | ||
RGS2 | Regulation of translation / cell cycle / spermatogenesis / regulation of G-protein coupled receptor protein signaling pathway / negative regulation of signal transduction / negative regulation of phospholipase activity / negative regulation of cardiac muscle hypertrophy / termination of G-protein coupled receptor signaling pathway / negative regulation of mitogen-activated protein (MAP) kinase activity / positive regulation of GTPase activity / negative regulation of G-protein coupled receptor protein signaling pathway / brown fat cell differentiation / relaxation of cardiac muscle / relaxation of vascular smooth muscle / positive regulation of cardiac muscle contraction / regulation of adrenergic receptor signaling pathway | 0.007 | 14.51 | 202388_at |
RGS3 | Inactivation of mitogen-activated protein kinase (MAPK) activity / signal transduction / regulation of G-protein coupled receptor protein signaling pathway / negative regulation of signal transduction / termination of G-protein coupled receptor signaling pathway / positive regulation of GTPase activity | 1.00E-05 | 0.39 | 203823_at |
RGS4 | Inactivation of MAPK activity / regulation of G-protein coupled receptor protein signaling pathway / negative regulation of signal transduction / termination of G-protein coupled receptor signaling pathway / positive regulation of GTPase activity | 3.00E-04 | 0.17 | 204337_at |
0.003 | 0.11 | 204338_s_at | ||
0.004 | 0.14 | 204339_s_at | ||
RGS5 | Signal transduction / regulation of G-protein coupled receptor protein signaling pathway / negative regulation of signal transduction / termination of G-protein coupled receptor signaling pathway / positive regulation of GTPase activity | 0.01 | 47.79 | 209070_s_at |
0.008 | 81.82 | 209071_s_at | ||
0.009 | 95.52 | 218353_at | ||
RGS10 | Negative regulation of signal transduction / termination of G-protein coupled receptor signaling pathway / positive regulation of GTPase activity | 0.003 | 3.92 | 204319_s_at |
RGS19 | Autophagy / G-protein coupled receptor signaling pathway / small GTPase mediated signal transduction / negative regulation of signal transduction / termination of G-protein coupled receptor signaling pathway / positive regulation of GTPase activity | 9.00E-04 | 2.45 | 204336_s_at |
- Citation: Tanabe S, Aoyagi K, Yokozaki H, Sasaki H. Regulated genes in mesenchymal stem cells and gastric cancer. World J Stem Cells 2015; 7(1): 208-222
- URL: https://www.wjgnet.com/1948-0210/full/v7/i1/208.htm
- DOI: https://dx.doi.org/10.4252/wjsc.v7.i1.208