Limbal stem cells: Central concepts of corneal epithelial homeostasis

Figure 1 Anatomy of the eye. The cornea (A) comprises the colourless front portion of the eye immediately anterior to the iris and pupil (B). The limbus, located at the corneoscleral junction (B) is the transitional zone where the corneal and conjuctival epithelia merge, is shown in section using Haematoxalin and Eosin stain (C) and is considered a reservoir of stem cells which migrate centripetally to form the 5-7 cell layer corneal epithelium (DAPI fluorescence to highlight cell nuclei in corneal section, D).