Kallikrein-kinin in stem cell therapy

doi:10.4252/wjsc.v6.i4.448

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Sep 26, 2014; 6(4): 448-457
Published online Sep 26, 2014. doi: 10.4252/wjsc.v6.i4.448

Table 1 Enhanced protection by stem cells genetically modified with tissue kallikrein

	Apoptosis	Inflammation	Oxidative stress	Tissue remodeling	Angiogenesis
TK-MSCs
Renal I/R[66]	↓	↓	↓	--	--
Lupus nephritis[74]	↓	↓	↓	--	--
MI[67]	↓	↓	--	↓	↑
TK-EPCs
MI[87]	↓	--	↓	--	↑
Limb ischemia[88]	--	--	--	--	↑

TK-MSCs: Tissue kallikrein-modified mesenchymal stem cells; I/R: Ischemia/reperfusion; MI: Myocardial infarction; TK-EPCs: Tissue kallikrein-modified endothelial progenitor cells.

Citation: Chao J, Bledsoe G, Chao L. Kallikrein-kinin in stem cell therapy. World J Stem Cells 2014; 6(4): 448-457
URL: https://www.wjgnet.com/1948-0210/full/v6/i4/448.htm
DOI: https://dx.doi.org/10.4252/wjsc.v6.i4.448