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©2014 Baishideng Publishing Group Inc.
World J Stem Cells. Sep 26, 2014; 6(4): 441-447
Published online Sep 26, 2014. doi: 10.4252/wjsc.v6.i4.441
Published online Sep 26, 2014. doi: 10.4252/wjsc.v6.i4.441
Table 1 Cancer stem cell markers and significance
| Cancer stem cell marker | Expression | Significance |
| CD44 | Hyaluronate receptor | Cell growth, differentiation, motility, increased chemoresistance, self-propagation |
| CD133 | Transmembrane glycoprotein | Increased tumor formation, increased chemoresistance, regeneration of original tumor cells |
| CD117 | Tyrosine kinase receptor | Cell signaling, apoptosis, cell differentiation, proliferation, cell adhesion |
| ALDH1A1 | Cell protector from aldehydes | Regeneration of tumor cells, chemoresistance |
| EpCAM (CD326) | Transmembrane glycoprotein | Cell adhesion, cell proliferation, tumor formation, epithelial to mesenchymal transition |
| CD24 | Transmembrane glycoprotein | Cell adhesion, aggressive phenotype, metastasis |
- Citation: Haygood CLW, Arend RC, Straughn JM, Buchsbaum DJ. Ovarian cancer stem cells: Can targeted therapy lead to improved progression-free survival? World J Stem Cells 2014; 6(4): 441-447
- URL: https://www.wjgnet.com/1948-0210/full/v6/i4/441.htm
- DOI: https://dx.doi.org/10.4252/wjsc.v6.i4.441