Haploidentical vs cord blood transplantation for adults with acute myelogenous leukemia

doi:10.4252/wjsc.v6.i4.371

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Sep 26, 2014 (publication date) through Jun 29, 2024

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World Journal of Stem Cells

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1948-0210

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World J Stem Cells. Sep 26, 2014; 6(4): 371-379
Published online Sep 26, 2014. doi: 10.4252/wjsc.v6.i4.371

Table 2 Haploidentical hematopoietic cell transplantation compared to transplantation from other graft sources

Year	Number of patients	Neutrophil engraftment (median d)	aGVHD II-IV (%)	cGVHD (%)	100 d NRM (%)	Relapse (2 yr)	Survival (%)
2002[63]	MUD BM 81	16	42	57	23	25	58 (2 yr OS)
	MMUD BM 58	15	33	51	45	26	34
	Haplo 48	14	46	50	42	42	21
2005[53]	Haplo-ALL 74	NA	8	NA	49	38	13 (2 yr LFS)
	UCB-ALL 91		26		41	23	36
	Haplo-AML 151		12		58	18	24
	UCB-AML 91		26		24	24	30
2009[48]	Haplo 56	54/56 (13)	27	23	13	22	68 (2 yr LFS)
2009[48]	MRD 51	48/51 (12)	14	31	8	17	76

aGVHD: Acute graft versus host disease; cGVHD: Chronic graft versus host disease; NRM: Non-relapse mortality; AML: Acute myelogenous leukemia; ALL: Acute lymphoblastic leukemia; NA: Not available; HCT: Hematopoietic cell transplant; MUD: Matched unrelated donor; BM: Bone marrow; MMUD: Mismatched unrelated donor; Haplo: Haploidentical family donor; OS: Overall survival; LFS: Leukemia free survival; UCB: Umbilical cord blood; MRD: Matched related donor.

Citation: Solh M. Haploidentical vs cord blood transplantation for adults with acute myelogenous leukemia. World J Stem Cells 2014; 6(4): 371-379
URL: https://www.wjgnet.com/1948-0210/full/v6/i4/371.htm
DOI: https://dx.doi.org/10.4252/wjsc.v6.i4.371