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Copyright ©2014 Baishideng Publishing Group Inc.
World J Stem Cells. Jul 26, 2014; 6(3): 367-370
Published online Jul 26, 2014. doi: 10.4252/wjsc.v6.i3.367
Table 1 Immunophenotype and differentiation potential comparison between umbilical cord matrix derived fibroblasts and bone-marrow-mesenchymal stem cells
ImmunophenotypeGene expressionDifferentiation potential
BM-MSCPositive for:CD90, CD73, CD105, CD13, CD44[1]CTSB, CTSD, PHB[10], BSP[7], Leptin[12]No report for osteo-, adipo or chondrogenic differentiation failure
SSEA-4, LNGFR[6], CD146+++[7]HOX-gene[7], DLK-1[16], pSmad2 (low and modulated)[12]
Negative for:CD14, CD34[1], CD56[7]
UC-MSCPositive for:CD90, CD73, CD105, CD13, CD44[1]PAI-1, MnSOD[10], HOX-gene (different expression pattern)[7]Reports for adipo-[13,15] and osteogenic[7,12] differentiation failure
CD56, CD146++[7]pSmad2 (high and constitutive)[12]
Negative for:CD14, CD34[1], SSEA-4, LNGFR[6]CTSB, CTSD, PHB[10], BSP[7], Leptin[12], DLK-1 (or weakly)[16]