Copyright
©2014 Baishideng Publishing Group Inc.
World J Stem Cells. Jul 26, 2014; 6(3): 355-366
Published online Jul 26, 2014. doi: 10.4252/wjsc.v6.i3.355
Published online Jul 26, 2014. doi: 10.4252/wjsc.v6.i3.355
Table 3 Summary of clinical trials: Effect of heart failure on endothelial progenitor cells
Ref. | Subjects | EPCs (number/function) | Findings |
Valgimigli et al[28] | 45 healthy controls 91 CHF | CD34+, CD34+/CD133+/KDR+ (flow cytometry) | CD34+ and CD34+/CD133+/KDR+ are significantly elevated in CHF patients compared to controls EPC number is negatively correlated with NYHA functional class |
Nonaka-Sarukawa et al[29] | 22 healthy controls 16 mild CHF 10 severe CHF | CD34+ (flow cytometry) | CD34+ is significantly higher in mild CHF compared to severe CHF |
Michowitz et al[30] | 107 CHF | CFU | CFU is the independent predictor for CHF CFU is also negatively correlated with NYHA functional class |
- Citation: Lee PSS, Poh KK. Endothelial progenitor cells in cardiovascular diseases. World J Stem Cells 2014; 6(3): 355-366
- URL: https://www.wjgnet.com/1948-0210/full/v6/i3/355.htm
- DOI: https://dx.doi.org/10.4252/wjsc.v6.i3.355