Differentiation of mesenchymal stem cells into gonad and adrenal steroidogenic cells

doi:10.4252/wjsc.v6.i2.203

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Apr 26, 2014; 6(2): 203-212
Published online Apr 26, 2014. doi: 10.4252/wjsc.v6.i2.203

Table 2 Properties of steroidogenic cells derived from mesenchymal stem cells induced by steroidogenic factor-1/liver receptor homolog-1 and cAMP

Cells	Origin	SF-1/LRH-1	Produced	Properties of differentiated cells
KUM9	Mouse	Plasmid	Testosterone	Testicular leydig cells
KUM9	Bone marrow	Plasmid	Testosterone	Testicular leydig cells
hMSC-TERT-E6/7	Human	Plasmid	Cortisol	Adrenal fasciculata cells
hMSC-TERT-E6/7	Bone marrow	Retrovirus	Cortisol
UE7T-13	HumanBone marrow	Retrovirus	Testosterone, cortisol	Fetal adrenal-like cells
UE6E7T-12		Retrovirus	Testosterone, cortisol
UE6E7T-11		Retrovirus	Testosterone, cortisol
UCB408E6E7T-33	Human	Retrovirus	Progesterone cells	Ovarian granulosa-luteal cells
UCB408E6E7T-33	Umbilical cord blood	Retrovirus	Progesterone cells	Ovarian granulosa-luteal cells

Citation: Yazawa T, Imamichi Y, Miyamoto K, Umezawa A, Taniguchi T. Differentiation of mesenchymal stem cells into gonad and adrenal steroidogenic cells. World J Stem Cells 2014; 6(2): 203-212
URL: https://www.wjgnet.com/1948-0210/full/v6/i2/203.htm
DOI: https://dx.doi.org/10.4252/wjsc.v6.i2.203