Mesenchymal stem cells in the treatment of spinal cord injuries: A review

Table 4 Changes in the expression of caspase-related and nuclear factor-κB-related apoptotic genes after spinal cord injury

UniGene	GenBank	Gene name	Fold change after SCI	Fold change after hUCBSC treatment
Rn. 37508	NM_012762	Casp1	9.14 ± 1.70	1.27 ± 0.78
Rn. 81078	NM_130422	Casp12	2.91 ± 1.34	1.46 ± 0.68
Rn. 10562	NM_012922	Casp3	3.56 ± 0.92	1.18 ± 0.84
Rn. 88160	NM_031775	Casp6	3.34 ± 1.06	1.46 ± 0.79
Rn. 53995	NM_022260	Casp7	2.81 ± 1.27	2.81 ± 1.21
Rn. 54474	NM_022277	Casp8	3.84 ± 1.20	1.62 ± 0.89
Rn. 32199	NM_031632	Casp9	2.86 ± 0.71	1.36 ± 0.62
Rn. 67077	NM_053362	Dffb (Cad)	32.94 ± 0.78	2.72 ± 0.84
Rn. 16183	NM_152937	Fadd	2.21 ± 0.78	1.51 ± 0.73
Rn. 162521	NM_139194	Tnfrsf6 (Fas)	10.87 ± 1.77	1.79 ± 0.67
Rn. 44218	NM_053353	CD40lg	15.91 ± 0.99	3.46 ± 0.78
Rn. 160577	NM_080769	Lta (Tnfb)	28.67 ± 0.07	2.06 ± 0.68
Rn. 2275	NM_012675	TNF-α	7.17 ± 1.63	2.36 ± 1.03
Rn. 11119	NM_013091	Tnfrsf1a (TNFR1)	2.53 ± 1.48	1.22 ± 0.78
Rn. 83633	NM_130426	Tnfrsf1b (TNFR2)	5.25 ± 1.56	3.01 ± 0.99
Rn. 25180	NM_134360	Tnfrsf5 (CD40)	4.26 ± 1.84	1.99 ± 0.78
Rn. 54443	NM_030989	Tp53 (P53)	3.46 ± 1.41	-1.12 ± 0.61
Rn. 18545	XM_341671	Tradd	5.62 ± 1.13	1.46 ± 0.59
Rn. 136874	AI406530	Traf1	4.12 ± 1.34	2.06 ± 0.84

Results are expressed as mean ± SD. hUCBSC: Human umbilical cord blood stem cells; NF-κB: Nuclear factor-κB; SCI: Spinal cord injury. Refer Dasari et al[75].