Advances in homology directed genetic engineering of human pluripotent and adult stem cells

doi:10.4252/wjsc.v5.i4.98

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Oct 26, 2013 (publication date) through Nov 27, 2024

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Oct 26, 2013; 5(4): 98-105
Published online Oct 26, 2013. doi: 10.4252/wjsc.v5.i4.98

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Figure 2 Barriers to gene targeting. The different barriers that gene delivery vectors must overcome for successful gene targeting include cell binding and internalization, intracellular trafficking and endosomal escape, translocation through the nuclear envelope, and efficient site-specific integration.

Citation: Ramamoorthi K, Curtis D, Asuri P. Advances in homology directed genetic engineering of human pluripotent and adult stem cells. World J Stem Cells 2013; 5(4): 98-105
URL: https://www.wjgnet.com/1948-0210/full/v5/i4/98.htm
DOI: https://dx.doi.org/10.4252/wjsc.v5.i4.98