Neural stem cells isolated from amyloid precursor protein-mutated mice for drug discovery

Table 2 Genotype-dependent cell yield per animal

	Wild type	Tg2576
Primary neurospheres	1.7 × 105± 5 × 104	1.7 × 105± 1×104
Secondary neurospheres	1.7 × 105± 1.4× 104	1.3×105± 9.7×103a

Cells obtained from 4 animals were counted in primary and secondary neurospheres development. A decrease in the total number of cells per animal in Tg2576-compared to Wt culture was observed, ^aP < 0.05. Statistical studies performed by Student’s t-test.