Human adipose tissue contains erythroid progenitors expressing fetal hemoglobin

doi:10.4252/wjsc.v5.i4.205

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Oct 26, 2013; 5(4): 205-216
Published online Oct 26, 2013. doi: 10.4252/wjsc.v5.i4.205

Table 2 Mean fluorescence intensity of fetal hemoglobin and adult hemoglobin in hemoglobin-expressing erythroid cells

		HbF		HbA		HbF/HbF+HbA
		HbF⁺HbA^- cells	HbF⁺HbA⁺ cells	HbF^-HbA⁺ cells	HbF⁺HbA⁺ cells
CB CD34⁺ cells	A	124082 ± 10917	204968 ± 17070^b	22139 ± 4457^a	25171 ± 3211^a	8.49 ± 1.40
	B	16989 ± 1382	21627 ± 1027	6139 ± 182^a	5248 ± 398^a	5.58 ± 0.38
PB CD34⁺ cells			23495 ± 1326	10746 ± 893	9496 ± 548	1.26 ± 0.14
SVF CD45^- cells	A	90164 ± 23126	78566 ± 2697^b^c^f	28229 ± 5204^a	21022 ± 3720^a	3.86 ± 0.71
	B	34612 ± 2701^c	29051 ± 1514	9637 ± 1094	5433 ± 325^a	5.92 ± 1.10
SVF CD45⁺ cells	A	61429 ± 4085^c	47907 ± 2011^b^d	16388 ± 986	16668 ± 587^a	3.53 ± 0.18
	B	20971 ± 4696	15731 ± 1875	8006 ± 1653	9219 ± 1533	3.46 ± 1.03

The mean fluorescence intensity values are expressed as the mean ± SE and correspond to the samples analyzed in Figure 2. Statistical significance:

^aP < 0.05,

^bP < 0.01 vs PB CD34⁺ cells;

^cP < 0.05,

^dP < 0.01 vs CB CD34⁺ cells;

^fP < 0. 05 CD45⁺ cells vs CD45^- cells. SVF: Stromal vascular fraction; CB: Cord blood; PB: Peripheral blood; HbF: Fetal hemoglobin; HbA: Adult hemoglobin.

Citation: Navarro A, Carbonell-Uberos F, Marín S, Miñana MD. Human adipose tissue contains erythroid progenitors expressing fetal hemoglobin. World J Stem Cells 2013; 5(4): 205-216
URL: https://www.wjgnet.com/1948-0210/full/v5/i4/205.htm
DOI: https://dx.doi.org/10.4252/wjsc.v5.i4.205