A familiar stranger: CD34 expression and putative functions in SVF cells of adipose tissue

Figure 1 Protein structure of the CD34 family. CD34, podocalixin and endoglycan are transmembrane proteins which display O-glycosylated and sialylated serine-,threonine- and proline-rich extracellular mucin domain, putative sites of N-glycosylation, a cysteine-containing globular domain and a juxtamembrane stalk region. NHERF1 and 2 bind to the C-terminal tail of podocalyxin and endoglycan but not CD34. Conversely the CrkL selectively binds to a distinct juxtamembrane sequence in CD34.