Umbilical cord blood mesenchymal stem cells protect amyloid-β42 neurotoxicity via paracrine

Figure 2 Recombinant progranulin and decroin protect against amyloid-β42-neurotoxicity in vitro. A: Instead of human umbilical cord blood-derived mesenchymal stem cells, 10 ng of progranulin and decroin were used to treat amyloid-β42 (Aβ42)-exposed rat primary neuronal cells, After 36 h, each cell was assayed by Live/Dead staining. The green and red colorindicate live and dead cells, respectively; B: Percentage of dead cells in decroin- and progranulin-treated cells exposed to Aβ42; C: To show survived neurons in rat primary neuronal cells, cells were stained by anti-microtubule associated protein 2 antibody. PGRN: Progranulin; DCN: Decorin.