Human umbilical cord mesenchymal stem cells as treatment of adjuvant rheumatoid arthritis in a rat model

Figure 5 Inhibition of inflammatory responses in rats with complete freunds adjuvant induced arthritis after treatment with human umbilical cord blood-derived mesenchymal stem cells. A: Levels of tumor necrosis factor (TNF)-α, interleukin (IL)-1, and interferon (IFN)-γ in the sera of rats in positive control (PC) group, methotrexate (MTX) group, mesenchymal stem cell (MSC) group and hematopoietic (CD34+) stem cell (HSC) group obtained on day 34; B: Serum level of IL-10 obtained from different groups on day 34. ^aP < 0.05 MSC vs control and MTX groups; ^cP < 0.05 HSC vs control and MTX groups.