Immune regulatory properties of multipotent mesenchymal stromal cells: Where do we stand?

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Jan 26, 2011 (publication date) through Nov 23, 2024

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Jan 26, 2011; 3(1): 1-8
Published online Jan 26, 2011. doi: 10.4252/wjsc.v3.i1.1

Table 1 Potential candidates responsible for immunoregulation by mesenchymal stromal cells

Soluble factors	Measured response	Ref.
TGF-β and/or HGF	Proliferation, IFN-γ production	[25]
IDO	Proliferation	[40]
PGE2	Proliferation, IFN-γ and TNF-α production	[26,42]
HLA-G5	Proliferation and expansion of CD4+CD25+Foxp3+ regulatory T cells	[33]

TGF: Transforming growth factor; HGF: Hepatocyte growth factor; IDO: Indoleamine 2,3-dioxygenase; IFN: Interferon; TNF: Tumor necrosis factor.

Citation: Bassi ÊJ, Aita CAM, Câmara NOS. Immune regulatory properties of multipotent mesenchymal stromal cells: Where do we stand? World J Stem Cells 2011; 3(1): 1-8
URL: https://www.wjgnet.com/1948-0210/full/v3/i1/1.htm
DOI: https://dx.doi.org/10.4252/wjsc.v3.i1.1