RNA interference-mediated osteoprotegerin silencing increases the receptor activator of nuclear factor-kappa B ligand/osteoprotegerin ratio and promotes osteoclastogenesis

Figure 2 MTT assay to detect changes in cell proliferation in each group. The cell proliferation growth curves for each group were plotted with time on the X-axis and absorbance (A value) on the Y-axis. The experimental group, “shOPG”, represents osteoprotegerin gene-silenced bone marrow-derived mesenchymal stem cells (BMSCs) transfected with shOPG. The control group, “shScr”, consists of BMSCs transfected with a scrambling vector, while the “control” group includes untreated BMSCs.