MiR-21-5p-enriched exosomes from hiPSC-derived cardiomyocytes exhibit superior cardiac repair efficacy compared to hiPSC-derived exosomes in a murine MI model

doi:10.4252/wjsc.v17.i3.101454

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Mar 26, 2025 (publication date) through Apr 6, 2025

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Mar 26, 2025; 17(3): 101454
Published online Mar 26, 2025. doi: 10.4252/wjsc.v17.i3.101454

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Figure 1 Characterization of human-induced pluripotent stem cells and human-induced pluripotent stem cell-derived cardiomyocyte exosomes. A and B: The size was assessed utilizing nanoparticle tracking analysis; C and D: Morphology of human-induced pluripotent stem cells (hiPSCs) and human-induced pluripotent SC-derived cardiomyocyte exosomes (hiPSC-CM-exos) was analyzed via electron microscopy; E: Western blot analysis confirmed the expression of cluster of differentiation 63 (CD63) and tumor susceptibility gene 101 in exos derived from hiPSCs and hiPSC-CMs. iPSC-exos: Induced pluripotent stem cell-derived exosomes.

Citation: Jin JJ, Liu RH, Chen JY, Wang K, Han JY, Nie DS, Gong YQ, Lin B, Weng GX. MiR-21-5p-enriched exosomes from hiPSC-derived cardiomyocytes exhibit superior cardiac repair efficacy compared to hiPSC-derived exosomes in a murine MI model. World J Stem Cells 2025; 17(3): 101454
URL: https://www.wjgnet.com/1948-0210/full/v17/i3/101454.htm
DOI: https://dx.doi.org/10.4252/wjsc.v17.i3.101454