Asthma and stem cell therapy

doi:10.4252/wjsc.v17.i2.103599

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Feb 26, 2025 (publication date) through Feb 24, 2025

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Feb 26, 2025; 17(2): 103599
Published online Feb 26, 2025. doi: 10.4252/wjsc.v17.i2.103599

Table 2 Brief description of four clinical asthma trials related to stem cells in the clinical trials database

NCT No	Title	Disease	Source MSCs	Auto/Allo?	Delivery	Phases	Enrollment	Ages eligible for study	Locations
02192736	Safety and feasibility study of intranasal MTF for treatment of asthma	Asthma	UCMSC-CM	Allogeneic	Intra-nasal	1/2	20	18-65 years old	Panama
03137199	Allogeneic human MSCs via intravenous delivery in patients with mild asthma	Asthma	BMSCs	Allogeneic	IV	1	6	18-65 years old	United States
04883320	Stem cell strategies for the treatment of chronic asthma	Asthma	MSC	Unspecified	Not provided	Not applicable	15	18-70 years old	United Kingdom
05147688	Safety of cultured allogeneic adult umbilical cord-derived mesenchymal stem cells for pulmonary diseases	Pulmonary diseases, asthma	UCMSC	Allogeneic	IV	1	20	Child, adult, older adult	Antigua and Barbuda

BMSCs: Bone marrow mesenchymal stem cells; MSC: Mesenchymal stem cell; MTF: Mesenchymal trophic factor; UCMSC-CM: Conditioned medium prepared from umbilical cord mesenchymal stem cell; UCMSC: Umbilical cord mesenchymal stem cell.

Citation: Chen QH, Zheng JY, Wang DC. Asthma and stem cell therapy. World J Stem Cells 2025; 17(2): 103599
URL: https://www.wjgnet.com/1948-0210/full/v17/i2/103599.htm
DOI: https://dx.doi.org/10.4252/wjsc.v17.i2.103599