Effect of adipose-derived stem cells exosomes cross-linked chitosan-αβ-glycerophosphate thermosensitive hydrogel on deep burn wounds

Figure 4 Impact of chitosan-αβ-glycerophosphate hydrogel cross-linked with adipose-derived stem cell exosome on wound macrophages. A: The expression of interleukin-1α and CD86 in the chitosan + adipose-derived stem cell exosomes group is lower compared to the control group, while the expression of C-C motif chemokine ligand 22 and CD163 is higher; B: Western blotting analysis of nuclear factor κB pathway-related protein expression; C: Quantification of nuclear factor κB pathway-related proteins. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. ASC-Exos: Adipose-derived stem cell exosomes; CS: Chitosan; IL: Interleukin; CCL22: C-C motif chemokine ligand 22; IκBα: Inhibitor of kappa Balpha.