Fetal mice dermal mesenchymal stem cells promote wound healing by inducing M2 type macrophage polarization

Figure 2 Fetal dermal mesenchymal stem cells facilitate the phenotypic switch of RAW264. 7 from M1 to M2 type. A: Quantitative reverse transcriptase polymerase chain reaction analysis of genes characterizing M1, including interleukin-6 and inducible nitric oxide synthase, and the anti-inflammatory factor interleukin-10; B and C: Cells were immunostained with PE-CD86 and FITC-CD206 antibodies and analyzed by flow cytometry. ^aP < 0.05. IL: Interleukin; iNOS: Inducible nitric oxide synthase; FDMSC: Fetal dermal mesenchymal stem cell.