Outcomes of combined mitochondria and mesenchymal stem cells-derived exosome therapy in rat acute respiratory distress syndrome and sepsis

Figure 3 Protein expressions of cellular junctions, relative mitochondrial DNA expression and adenosine triphosphate concentration. A: Relative mitochondrial DNA expression, control vs other groups with different letters, ^aP < 0.01, ^bP < 0.05, ^cP < 0.001 (n = 6 for each group); B: Concentration level of adenosine triphosphate, control vs other groups with different letters, ^aP < 0.01, ^bP < 0.05, ^cP < 0.001 (n = 6 for each group); C: Protein expression of occludin, control vs other groups with different symbols, ^aP < 0.001, ^bP < 0.01; D: Protein expression of β-catenin, control vs other groups with different letters, ^aP < 0.001, ^bP < 0.01; E: Protein expression of zonula occludens-1, control vs other groups with different letters, ^aP < 0.001, ^bP < 0.01; F: Protein expression of E-cadherin, control vs other groups with different letters, ^aP < 0.001, ^bP < 0.01 (n = 4 for each group). All statistical analyses were performed by one-way ANOVA, followed by Bonferroni multiple comparison post hoc test. Grouping: L2 cells; L2 cells + hypoxia; L2 cells + mitochondria (100 μg); L2 cells + hypoxia + mitochondria (100 μg).