Hepatocyte growth factor enhances the ability of dental pulp stem cells to ameliorate atherosclerosis in apolipoprotein E-knockout mice

Figure 2 Neither Ad-Null modified dental pulp stem cells nor Ad-hepatocyte growth factor modified dental pulp stem cells altered the biochemical parameters of apolipoprotein E-knockout mice fed a high-fat diet. A: Serum concentrations of triglycerides, total cholesterol, low-density lipoprotein, and high-density lipoprotein in apolipoprotein E-knockout (ApoE^-/-) mice at weeks 6 and 12 (n = 4); B: Serum concentrations of glucose (GLU) and glycosylated serum protein (GSP) in ApoE^-/- mice at weeks 6 and 12 (n = 4); C: Body weight (n = 9). All results are presented as the means ± SEMs; ^bP < 0.01, ^cP < 0.001 vs. the normal fat diet group. ^eP < 0.01 vs. high-fat diet group. DPSC-Null: Ad-Null modified dental pulp stem cells; DPSC-HGF: Ad-hepatocyte growth factor modified dental pulp stem cells; HFD: High-fat diet; NFD: Normal formula diet; TG: Triglycerides; CHO: Cholesterol; LDL: Low-density lipoprotein; HDL: High-density lipoprotein; GLU: Glucose; GSP: Glycosylated serum protein.