Therapeutic potential of urine-derived stem cells in renal regeneration following acute kidney injury: A comparative analysis with mesenchymal stem cells

doi:10.4252/wjsc.v16.i5.525

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 16, Issue 5

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (701)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-8) series, Tables (1-1) series.

Item

Count

PDF

WORD

HTML

515

Figures (1-8)

Tables (1-1)

Sum=626

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

Download

Sum=47

May 26, 2024 (publication date) through Jun 29, 2024

Times Cited of This Article

Times Cited (0)

Journal Information of This Article

Publication Name

World Journal of Stem Cells

ISSN

1948-0210

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Basic Study

World J Stem Cells. May 26, 2024; 16(5): 525-537
Published online May 26, 2024. doi: 10.4252/wjsc.v16.i5.525

Table 1 Effects of urine-derived stem cells and bone marrow mesenchymal stem cells on renal morphology and tubular apoptosis

	AKI	AKI + USCs	AKI + BMSCs	Control
Cast (n/hpf)	6.12 ± 3.12	1.24 ± 1.12^a	1.53 ± 0.32^b	0
Necrosis (n/hpf)	4.35 ± 3.19	1.65 ± 1.17^a	0.85 ± 0.27^b	0
TUNEL-positive cells (n/hpf)	19.8 ± 13.2	4.02 ± 1.21^a	8.14 ± 3.5^b	0

^aP < 0.05 for urine-derived stem cell injection versus untreated acute kidney injury.

^bP < 0.05 for bone marrow mesenchymal stem cell injection versus untreated acute kidney injury.

Comparison of urine-derived stem cell or bone marrow mesenchymal stem cell injection on tubular morphology and apoptosis on day 5 after acute kidney injury induction. Numbers in the table represent the mean ± SD of tubular casts and necrotic tubules and of apoptotic cells detected by terminal deoxynucleotidyl transferase dUTP nick-end labeling, observed under high power (magnification, 400 ×). AKI: Acute kidney injury; USC: Urine-derived stem cell; BMSC: Bone marrow mesenchymal stem cell; TUNEL: Terminal deoxynucleotidyl transferase dUTP nick-end labeling; hpf: High-powered field.

Citation: Li F, Zhao B, Zhang L, Chen GQ, Zhu L, Feng XL, Gong MJ, Hu CC, Zhang YY, Li M, Liu YQ. Therapeutic potential of urine-derived stem cells in renal regeneration following acute kidney injury: A comparative analysis with mesenchymal stem cells. World J Stem Cells 2024; 16(5): 525-537
URL: https://www.wjgnet.com/1948-0210/full/v16/i5/525.htm
DOI: https://dx.doi.org/10.4252/wjsc.v16.i5.525