Low-intensity pulsed ultrasound reduces alveolar bone resorption during orthodontic treatment via Lamin A/C-Yes-associated protein axis in stem cells

Figure 6 Low-intensity pulsed ultrasound reverses the stress-induced decrease in LaminA/C, F-actin, and Yes-associated protein expression. A: Representative immunofluorescence images of F-actin (red), LaminA/C (green), and DAPI (blue) staining (left) and statistical analyses (middle), as well as representative 3D merged images constructed with Imaris software (right); B: Representative immunofluorescence images of Yes-associated protein (YAP1) (red) and DAPI (blue) staining (left) and statistical analyses (right); C: YAP1 protein expression analyzed by Western blotting; D: Representative images of immunohistochemical staining for YAP1 (left) and statistical analysis (right). ^aP < 0.05 vs control group, ^bP < 0.01 vs control group. LIPUS: Low-intensity pulsed ultrasound; YAP1: Yes-associated protein.