High glucose microenvironment and human mesenchymal stem cell behavior

doi:10.4252/wjsc.v16.i3.237

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Mar 26, 2024 (publication date) through Nov 2, 2024

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Mar 26, 2024; 16(3): 237-244
Published online Mar 26, 2024. doi: 10.4252/wjsc.v16.i3.237

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Figure 1 Glucotoxicity in mesenchymal stem cells exposed to high glucose culture conditions and hyperglycemia. AGE: Advanced glycation end product; AMPK: AMP-activated protein kinase; CXCR: C-X-C chemokine receptor type 4; drp1: Dynamin-related protein 1; fis1: Fission protein 1. mfn1: Mitofusin 1; MSC: Mesenchymal stem cell; mTOR: Mammalian target of rapamycin; PI3K: Phosphoinositide 3-kinase; ROS: Reactive oxygen species; TNF: Tumor necrosis factor; TSC1: Tuberous sclerosis 1.

Citation: Mateen MA, Alaagib N, Haider KH. High glucose microenvironment and human mesenchymal stem cell behavior. World J Stem Cells 2024; 16(3): 237-244
URL: https://www.wjgnet.com/1948-0210/full/v16/i3/237.htm
DOI: https://dx.doi.org/10.4252/wjsc.v16.i3.237