Long-term outcome of stem cell transplantation with and without anti-tumor necrotic factor therapy in perianal fistula with Crohn’s disease

Table 2 Fistula closure and recurrence, n (%)

	Total	Anti-TNF (n = 27)	Without anti-TNF (n = 38)	P value
Cumulative closure rate	50/65 (76.9%)	18/27 (66.7%)	32/38 (84.2%)	0.098
1-yr	43 (66.2)	17 (63.0)	26 (68.4)
2-yr	48 (73.8)	18 (66.7)	30 (78.9)
3-yr	49 (75.4)	-	31 (81.6)
Closure time (months)	6.94 ± 9.68	4.56 ± 4.37	8.28 ± 11.52	0.195
Cumulative recurrence rate	7/50 (14.0)	3/18 (16.7)	4/32 (12.5)	0.684
1-yr	4 (8.0)	2 (11.1)	2 (6.3)
2-yr	5 (10.0)	3 (16.7)	2 (6.3)
3-yr	7 (14.0)	-	4 (12.5)
Recurrence time (months)	16.57 ± 19.38	7.33 ± 7.77	23.50 ± 23.70	0.316

TNF: Tumor necrotic factor.