Therapeutic utility of human umbilical cord-derived mesenchymal stem cells-based approaches in pulmonary diseases: Recent advancements and prospects

Table 4 Clinical trials of umbilical cord mesenchymal stem cells therapy for patients with chronic obstructive pulmonary disease

No	Trial ID	UC-MSCs administration protocol			Phase	Status	Patients	Age (yr)	Follow-up time	Mask	Allocation	Country
		Frequency	Dose (cells)	Route
1	NCT04433104	2 (at mo 1 and 4)	1 × 106/kg	IV	II	Unknown	40	40-75	12 months	Single-blind	Non-Randomized	Vietnam
2	NCT04206007	1	N/A	IV	I	Active, not recruiting	9	40-75	48 months	Open label	N/A	China
3	NCT05147688	1	1 × 108	IV	I	Recruiting	20	Child, adult, older adult	48 months	Open-label	N/A	Antigua and Barbuda

UC-MSCs: Umbilical cord mesenchymal stem cells; IV: Intravenous; N/A: Not available.