Preliminary evidence of renal function improvement in chronic progressive kidney disease using autologous CD34+ cell therapy: A clinical trial

Figure 1 The change of estimated glomerular filtration rate before and after cell therapy. The estimated glomerular filtration rate (eGFR) slope reversed from negative to positive inclination in case 2, 3, and 4 after 1^st cell therapy. The improved eGFR after 1^st cell therapy was almost maintained after 2^nd cell therapy for three months. eGFR slope slightly improved after 1^st cell therapy in case 1 (patient with the lowest eGFR, highest amount of proteinuria, and lowest purity of administered CD34⁺ cells among four patients). However, it did not change to positive inclination. eGFR: Estimated glomerular filtration rate.