Enhanced wound healing and hemostasis with exosome-loaded gelatin sponges from human umbilical cord mesenchymal stem cells

Figure 7 Gelatin sponge loaded with exosomes promotes collagen formation, cell proliferation, and angiogenesis during the wound healing process. A: Masson-stained wound tissue sections as observed. Scale bar = 100 μm; B: Statistical analysis of the percentage of collagen volume with respect to tissue volume; C: CD31-positive vessels in wound tissue sections. Scale bar = 100 μm; D: Statistical analysis of CD31-positive vessels; E: Ki67-positive cells in wound tissue sections. Scale bar = 50 μm; F: Statistical analysis of Ki67 positive cell area percentage. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001, ^dP < 0.0001. Exo: Exosome.