Mechanism of adipose-derived mesenchymal stem cell exosomes in the treatment of heart failure

doi:10.4252/wjsc.v15.i9.897

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Sep 26, 2023 (publication date) through Dec 28, 2024

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Sep 26, 2023; 15(9): 897-907
Published online Sep 26, 2023. doi: 10.4252/wjsc.v15.i9.897

Table 1 Comparison of left ejection fraction, left ventricular fractional shortening and stroke volume in each group (mean ± SD, %)

Group	n	LVEF	LVFS	SV
Control group	10	83.26 ± 3.41	50.01 ± 2.63	0.27 ± 0.03
HF group	10	40.16 ± 2.37^a	28.65 ± 1.84^a	0.13 ± 0.02^a
ADSCs - exobiology group	10	70.85 ± 2.86^a^,^b	40.27 ± 2.16^a^,^b	0.22 ± 0.03^a^,^b
F value		580.8	229.2	68.64
P value		< 0.0001	< 0.0001	< 0.0001

^aP < 0.05, compared to control group.

^bP < 0.05, compared with heart failure group.

ADSC: Adipose-derived stem cells; HF: Heart failure; LVEF: Left ejection fraction; LVFS: Left ventricular fractional shortening; SV: Stroke volume.

Citation: Wang L, Zhang JJ, Wang SS, Li L. Mechanism of adipose-derived mesenchymal stem cell exosomes in the treatment of heart failure. World J Stem Cells 2023; 15(9): 897-907
URL: https://www.wjgnet.com/1948-0210/full/v15/i9/897.htm
DOI: https://dx.doi.org/10.4252/wjsc.v15.i9.897