Quercetin ameliorates oxidative stress-induced senescence in rat nucleus pulposus-derived mesenchymal stem cells via the miR-34a-5p/SIRT1 axis

doi:10.4252/wjsc.v15.i8.842

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Aug 26, 2023 (publication date) through Jan 18, 2025

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. Aug 26, 2023; 15(8): 842-865
Published online Aug 26, 2023. doi: 10.4252/wjsc.v15.i8.842

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Figure 13 Schematic representation of the mode of action of quercetin. Quercetin ameliorates oxidative stress-induced senescence in nucleus pulposus-derived mesenchymal stem cells via miR-34a-5p/SIRT1 axis. HE: Hematoxylin-eosin; NP: Nucleus pulposus; AF: Annulus fibrosus; IVD: Intervertebral disc; TBHP: Tert-butyl hydroperoxide; ROS: Reactive oxygen species assay. By Figdraw.

Citation: Zhao WJ, Liu X, Hu M, Zhang Y, Shi PZ, Wang JW, Lu XH, Cheng XF, Tao YP, Feng XM, Wang YX, Zhang L. Quercetin ameliorates oxidative stress-induced senescence in rat nucleus pulposus-derived mesenchymal stem cells via the miR-34a-5p/SIRT1 axis. World J Stem Cells 2023; 15(8): 842-865
URL: https://www.wjgnet.com/1948-0210/full/v15/i8/842.htm
DOI: https://dx.doi.org/10.4252/wjsc.v15.i8.842