Transplantation of human induced pluripotent stem cell derived keratinocytes accelerates deep second-degree burn wound healing

Figure 8 COL7A1 inhibition reversed the inhibitory effect of human induced pluripotent stem cells derived keratinocytes on the NF-κB pathway in mouse burn wounds. A: The protein level of p-p65 in mouse wound tissues treated with hiPSCs-KCs, with or without COL7A1 shRNA transfection, was employed by Western blotting; B: The protein level of IκBα in mouse wound tissues treated with hiPSCs-KCs, with or without COL7A1 shRNA transfection, was employed by Western blotting. ^bP < 0.01. n = 10. PBS: Phosphate buffered saline; hiPSCs: Human induced pluripotent stem cells; KCs: Keratinocytes.