Basic Study
Copyright ©The Author(s) 2023.
World J Stem Cells. Jul 26, 2023; 15(7): 713-733
Published online Jul 26, 2023. doi: 10.4252/wjsc.v15.i7.713
Figure 5
Figure 5 COL7A1 knockdown abolishes the facilitative effect of human induced pluripotent stem cells derived keratinocytes on keratinocyte proliferation in mouse burn wounds. A: The Ki67 positive cells in burn wound tissues of each group were detected by immunostaining on the 14th postoperative day. scale bar: 200 µm; B: The statistical graph of the number of Ki67 positive cells; C: The proliferation ability of keratinocytes in each group was detected by EdU staining, scale bar: 100 µm; D: The proliferation ability of keratinocytes in each group was detected by EdU staining; E: Immunofluorescence estimate of the EdU and HLA levels in burn tissue of mice in each group. aP < 0.05, bP < 0.01. n = 10. PBS: Phosphate buffered saline; hiPSCs: Human induced pluripotent stem cells; KCs: Keratinocytes; HLA: Human leukocyte antigen.